A population analysis of pooled data from the two large controlled studies in patients with metastatic colorectal cancer (n=505) who were administered XELODA at 1250 mg/m2 twice a day indicated that gender (202 females and 303 males) and race (455 white/Caucasian patients, 22 black patients, and 28 patients of other race) have no influence on the pharmacokinetics of 5'-DFUR, 5-FU and FBAL.
This is all occurring because of technology improvements.
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Genital Herpes CausesGenital herpes is caused by the herpes simplex virus (HSV).
THE RISK OF SEVERE NEUROTOXIC REACTIONS IS SHARPLY INCREASED IN PATIENTS WITH IMPAIRED RENAL FUNCTION OR PRE-RENAL AZOTEMIA.
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Because coronary artery disease is common and may be unrecognized in patients receiving sotalol, abrupt discontinuation in patients with arrhythmias may unmask latent coronary insufficiency.
In this case, lidocaine and bretylium are unlikely to be of value, and other Class I antiarrhythmics (disopyramide, procainamide) are likely to exacerbate the situation.
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When used concomitantly, inhalation anesthetics and calcium antagonists, such as verapamil, should each be titrated carefully to avoid excessive cardiovascular depression.
The need for hip replacement instead of surgical pinning of the patient's own hip joint depends on the exact location of the break.
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Editors: Ivette Motola, MD, Staff Physician, Department of Emergency Medicine, Harvard Medical School; Francisco Talavera, PharmD, PhD, Senior Pharmacy Editor, eMedicine; James Kimo Takayesu, MD, Staff Physician, Department of Emergency Medicine, Brigham and Women's Hospital/Massachusetts General Hospital.
Loss of traction: Loss of traction occurs when the surface is wet or slick and a person slips or when the ground is uneven and a person trips.